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Best Gut Health Brands

Gut health has only become top of mind in the past 5 years, yet brands like Rmdy and Seed have been able to very quickly come out with highly researched and effective products to answer market demand. Fascinating businesses with incredible LTVs.
Beekeeper's Natural

Fill your medicine cabinet with clean & natural remedies (that actually work). Immune support to energy support.

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Armra

ARMRA makes a nutrient-rich colostrum concentrate that protects, restores, and enhances immune health and cellular performance. Sourced from grass-fed cow’s colostrum, their products contain over 400 bioactive nutrients that support immune function, gut health, skin vitality, and more. Using their proprietary Cold-Chain BioPotent Technology, ARMRA ensures the nutrients are preserved in their most potent and bioavailable form.

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Health-Ade

Health-Ade is brewed in Los Angeles and contains organic fermented kombucha packed with probiotics and healthy organic acids which are known to support a healthy gut. Health-Ade has also launched 3 new product SKUS Health-Ade Plus, Health-Ade Pop (a soda alternative with prebiotics), and Health-Ade Mixers (probiotic alcohol mixers).

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Goodles

Mac 'n' cheese just got a makeover. Co-founded by actress Gal Gadot, Goodles is a healthier macaroni and cheese alternative that has 15g of protein, 6g of fiber, prebiotics to support gut health, and 21 nutrients from organic plants.

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Rmdy

rmdy was created to give anyone with a gut a preventative & proactive solution for short + long term digestive health that is efficacious, convenient, and delicious.

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ZBiotics

ZBiotics® is an enhanced probiotic drink that breaks down an unwanted alcohol byproduct called acetaldehyde – the primary culprit behind rough mornings after drinking. Drink a ZBiotic just before going out or right before your first drink to enjoy the rest of your night and wake up feeling as good as new.

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Seed

Seed believes beneficial microbes can play a systems-wide role in human health. Their Daily Synbiotic is a gut health supplement that reflects a commitment to reclaim the term ‘probiotics’ for science and to establish a new standard.

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IKU

IKU makes plant-based meals delivered right to your door. Whether you want IKU for 3 meals a day or just a snack, there's an option for you. Its bestsellers include delicious meals like the caramelized onion tart, mushroom toor dahl, and spinach & eggplant lasagne. All you have to do is pop it into the microwave for 1 - 2.5 minutes and enjoy.

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ION

ION's all-natural and soil-derived microbiome support products are available for all your body's most vital barriers - gut to skin to sinuses.

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Unbloat

Unbloat, a Gateway X company, is a quickly growing DTC supplement brand that’s on a mission to conquer bloating. Its all-natural, robust, doctor-created formula addresses bloating at the root cause - the gut microbiome - leading to long term comfort and confidence. Thousands of women swear by Unbloat to beat bloating and support gut health once and for all.

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Spoiled Child

Intelligent skin and hair products that fight against aging and that your body actually needs.

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Cymbiotika

Cymbiotika is an online supplement store that focuses on natural and organic health products. They offer a wide range of supplements designed to support various health benefits, including fitness, energy, immunity, and heart health, utilizing clean, science-backed ingredients for optimal wellness.

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Table of contents

What Are Direct-To-Consumer (D2C/DTC) Gut Health Brands?

Direct-to-consumer (D2C/DTC) gut health brands are companies that specialize in products designed to improve gastrointestinal health, such as probiotics, prebiotics, and dietary supplements, and sell these products directly to consumers through online platforms. By bypassing traditional retail channels, these brands can offer personalized customer experiences, educational content about gut health, and innovative products tailored to individual health needs.

Brands like Seed, VSL#3, and Culturelle have become leaders in the D2C gut health space, recognized for their scientific approach to product development, transparency in ingredient sourcing, and commitment to customer education on gut health.

What Are The Best Direct-To-Consumer Gut Health Brands?

The best D2C gut health brands are distinguished by their commitment to scientific research, quality ingredients, and effective formulations. Seed stands out for its use of scientifically-backed probiotic strains in its Synbiotic formula, offering a well-researched approach to improving gut health. VSL#3 is notable for its high-potency probiotic medical food, used under medical supervision for managing conditions like IBS and ulcerative colitis.

Culturelle is widely recognized for its range of probiotics that cater to various health needs, from digestive support to immune health, leveraging clinically studied strains. These brands excel not only in providing high-quality gut health supplements but also in fostering informed communities around gut health and wellness.

What Are Current Trends In The Direct-To-Consumer Gut Health Category?

The D2C gut health category is currently witnessing several key trends that reflect a growing consumer interest in holistic health and wellness. Personalization is a major trend, with brands offering tailored probiotic and prebiotic formulations based on individual health assessments and gut microbiome testing.

Sustainability and clean labeling are also becoming increasingly important, as consumers seek products with transparent, environmentally friendly practices and ingredients. Furthermore, the integration of technology for enhanced customer engagement and education, such as mobile apps and interactive websites, is on the rise, allowing for a more interactive and informed approach to managing gut health. These trends underscore the shift towards more personalized, sustainable, and tech-driven solutions in the realm of gut health.

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